Methods According to the TCM theory that the spleen is responsible for keeping blood within the vessels, Warfarin, belonging to Dicoumarol family, is used to make a patho-bleeding model of rabbit, causing prothrombin time (PT) and bolus alba partial thromboplastin time (APTT) extending obviously, so it can be taken as the model of spleen failing to control blood.

方法针对中医“脾主统血”的功能,利用香豆素类药物华法林钠制造家兔病理性出血模型,引起凝血酶原时间(Prothrombin time,PT)、白陶土部分凝血活酶时间(activated partial thromboplastin time,APTT)的明显延长,作为“脾不统血”的模型。